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ESMO 2021 journaal | Upper GI-tumoren

29 min.

Prof. dr. Hanneke van Laarhoven bespreekt in dit journaal het belangrijkste ESMO-nieuws over Upper GI-tumoren. 

De volgende abstracts komen aan bod:

  1. The effect of hyperthermic intraperitoneal chemotherapy (HIPEC) upon cytoreductive surgery (CRS) in gastric cancer (GC) with synchronous peritoneal metastasis (PM): A randomized multicentre phase III trial (GASTRIPEC-I-trial)
  2. Nivolumab (NIVO) Plus Chemotherapy (Chemo) or Ipilimumab (IPI) vs Chemo as First-Line (1L) Treatment for Advanced Gastric Cancer/Gastroesophageal Junction Cancer/Esophageal Adenocarcinoma (GC/GEJC/EAC): CheckMate 649 Study
  3. Sintilimab plus chemotherapy (chemo) versus chemo as first-line treatment for advanced gastric or gastroesophageal junction (G/GEJ) adenocarcinoma (ORIENT-16): first results of a randomized, double-blind, phase 3 study
  4. Sintilimab plus chemotherapy versus chemotherapy as first-line therapy in patients with advanced or metastatic esophageal squamous cell cancer: First Results of the Phase 3 ORIENT-15 study
  5. JUPITER-06: A Randomized, Double-blind, Phase 3 Study of Toripalimab versus Placebo In Combination with First-Line Chemotherapy for Treatment Naive Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC)
  6. Ipilimumab or FOLFOX in combination with Nivolumab and Trastuzumab in previously untreated HER2 positive locally advanced or metastastic EsophagoGastric Adenocarcinoma (EGA) – results of the randomized phase 2 INTEGA trial (AIO STO 0217).
  7. CLDN 18.2-targeted CAR-T cell therapy in patients with cancers of the digestive system
  8. Primary Analysis of a Phase 2 Single-Arm Trial of Trastuzumab Deruxtecan (T-DXd) in Western Patients (Pts) With HER2-Positive (HER2+) Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Cancer Who Progressed on or After a Trastuzumab-containing Regimen
  9. Unicancer PRODIGE 24/CCTG PA6 trial: Updated results of a multicenter international randomized phase 3 trial of adjuvant mFOLFIRINOX (mFFX) versus gemcitabine (gem) in patients (pts) with resected pancreatic ductal adenocarcinomas (PDAC).
  10. Perioperative or only adjuvant nab-paclitaxel plus gemcitabine for resectable pancreatic cancer - results of the NEONAX trial, a randomized phase II AIO study

Bekijk hier het volledige overzicht van onze ESMO 2021 journaals en interviews.

Laatst bewerkt: 20-12-2023

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